BREAKING: $435 million has been liquidated from the cryptocurrency market in the past 12 hours.

Beating AI Express: Anthropic has built its own biology lab in the San Francisco Bay Area, moving its AI model Claude from digital research to real-world experiments. Eric Kauderer-Abrams, head of life sciences at Anthropic, confirmed the company now runs its own experiments while also outsourcing some work to external partners. The next step is integrating Claude directly into lab automation: Anthropic aims to have Claude control robotic arms, pipetting robots and other equipment, performing experiments independently under human supervision. Last month, the company launched the Model Hardware Standard, which allows AI to control microscopes, robotic arms and lab instruments via a unified interface. The system can already adjust parameters based on experimental results and even handle some equipment malfunctions. Anthropic has also begun conducting preclinical drug research, focusing on diseases that traditional pharmaceutical firms deem too difficult or not commercially viable. However, the company will not carry out human clinical trials for now, noting its lab is not specifically for drug discovery, to avoid direct competition with its pharmaceutical clients. Life sciences is one of the areas where Anthropic has allocated the most manpower and resources. In June this year, the company launched Claude Science, a workbench integrating research tools including paper databases, code and computing resources. Now, with the addition of a real lab, Claude’s scientific research capabilities are advancing from “data analysis” to “hands-on experimentation.”

Jiang Zhuoer, founder of LeBit Mining Pool, published an article titled "Will Interest Rate Hikes Kill the Crypto Bull Market?" The brief conclusion is that such hikes have minimal impact. The growth and internal cycles of the crypto sector far outweigh the influence of interest rate increases. BTC’s full historical chart shows that the 2013 and 2021 bull markets both advanced amid rate hikes or high interest rates, with the 2021 bull market especially facing the dual headwinds of high rates and balance sheet reduction. The crypto space’s ability to shrug off these unfavorable factors stems first from its high growth: a single bull market can deliver gains of over tenfold, making it indifferent to whether interest rates stand at 3% or 5%. Second, the total market capitalization of cryptocurrencies is just a fraction of that of U.S. stocks, so the impact of U.S. stocks diverting new funds exceeds that of the Federal Reserve’s balance sheet reduction.

Stimulated by the U.S. SEC’s new tokenized stock innovation exemption policy, gains in related beneficiary concept coins and stocks have expanded, with the rally spilling over to associated DeFi tokens and further impacting the altcoin market. According to HTX market data: UNI is trading at $9.14, up 35% in 24 hours; ARB at $0.207, up 26.7% in 24 hours; NEAR at $3.58, up 26.5% in 24 hours; STRK at $0.034, up 22.7% in 24 hours; RAY at $1.76, up 22% in 24 hours; INJ at $6.8, up 22.2% in 24 hours. Separately, per BIT (bit.com) market data, in the stock space: Securitize closed up 14.93% this morning, and rose an additional 7.8% in pre-market trading today; Robinhood closed up 5.16% this morning, with an extra 3.5% gain in pre-market trading today. For more details, see the report: "SEC’s Major Boost: Tokenized Stock Innovation Exemption – Which Products Qualify?"

According to HTX market data, HYPE has surged past $90 to set a new all-time high, with a 24-hour gain of 5.76%. Its market capitalization stands at $19.88 billion, ranking 8th on the cryptocurrency market cap leaderboard (excluding stablecoins).

With the official launch of Circle’s Arc mainnet, Kite announced it is collaborating with Circle to explore agent-to-agent service transactions built on Arc, covering service discovery, quoting, transaction agreement, delivery acceptance, and USDC payment settlement. According to the introduction, Kite is building a transaction process for buyers and sellers via its Kite Seller Console and Kite Agent Passport, enabling sellers to set service prices, delivery timelines, and acceptance criteria, while buyers can authorize payments within a preset spending cap, with an escrow mechanism linking delivery and settlement. In this setup, Kite handles service agreements and delivery workflows, while Arc provides the payment settlement network. To date, the relevant transaction process has been verified on the Arc testnet, and subsequent integration work is still underway.

Beating AI Express: Anthropic has leveraged Claude to optimize the performance of 36 open-source biological models. In under four weeks, these models achieved an average speedup of around 4x, covering tasks including protein structure prediction, protein design, and genomic analysis. All related optimization code has been open-sourced. Claude did more than just modify Python code; it also wrote custom GPU kernels like FlashPairformer, directly boosting GPU computing efficiency at the low level. In official tests, some previously time-consuming calculations sped up by up to 3.2x. For different models, Claude individually identified bottlenecks, eliminating redundant computations or pre-caching frequently used data. The entire process was overseen by two Anthropic biological modeling researchers, neither of whom had prior experience in inference optimization or kernel engineering. Even when requiring identical results before and after optimization, the models still delivered an average speedup of roughly 1.6x; when allowing minor, normal-range differences in model outputs, the average speedup reached about 4x. Previously, a single protein design experiment at Anthropic required up to ~2,500 H100 GPU hours per target. After optimization, one H200 can achieve comparable results in 24 hours, with total costs of around $150 for the GPU plus Claude. Experiments that once needed thousands of GPU hours can now be completed in roughly one day.